Breast cancer, early stage
Breast cancer, advanced or metastatic
Breast cancer, early stage
Breast cancer, advanced or metastatic
Available as 25 mg tablets. Tablets should NOT be broken or crushed. Store at room temperature.
Aromatase Inhibitor
Take with or without food
If a dose is missed, patients should be instructed to take it as soon as they remember, unless it is close to the next dose. If it close to the next dose, patients should skip the missed dose and resume with the next scheduled dose.
Common: Hot flashes, Arthralgia/myalgia, Fatigue.
Less Common: Edema, Nausea, Osteoporosis, Pathological fracture, Headache, Gynecologic symptoms (vaginal dryness, discharge, itching).
The adverse effects listed above are not exhaustive. Please refer to the relevant product monograph for full details.
Baseline before treatment: bone density before or after 2 to 3 month trial of therapy.
During treatment: Bone density (follow up every 3 years or as clinically indicated).
If clinically indicated: serum cholesterol, triglycerides.
BC Cancer. BC Cancer Drug Manual. Exemestane. Vancouver, British Columbia: BC Cancer Agency. Available at: http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Exemestane_monograph_1Dec2011_formatted.pdf. Updated December 1, 2010. Accessed January 22, 2024.
Lexicomp. Exemestane Monograph. In: Lexi-Drugs. Hudson, Ohio: Lexi-Comp, Inc. Available at: https://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/6887?cesid=3zMMu3CPnUr&searchUrl=%2Flco%2Faction%2Fsearch%3Fq%3Dexemestane%26t%3Dname%26acs%3Dfalse%26acq%3Dexemestane. Updated January 29, 2024. Accessed January 30, 2024.
Cancer Care Ontario. Exemestane Monograph. Drug Formulary. Toronto, Ontario: Cancer Care Ontario. Available at: https://www.cancercareontario.ca/en/drugformulary/drugs/monograph/43771. Updated November 2020. Accessed January 22, 2024.
Pharmacia & Upjohn Inc. Aromasin Product Monograph. Mississauga. Updated March 6, 2018.